Chemical shifts induced by aromatic solvent (ASIS) were observed (see Table) in the 1H NMR spectra of 1 in C6D6. All the ring protons, except H-4, H-23, H-11 and H-14 were shifted to higher field and the chemical shift difference DELTA (δ) = δHSolvt – δHC6D6 (solvt = CDCl3, CD2Cl2 etc) are given in Table. The use of aromatic solvents like C6D6 with high magnetic anisotropy instead of magnetic isotropic solvents such as CDCl3, CD2Cl2 etc results in upfield shift of all resonance signals of the ring.
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